Intelligence Quotient at the Age of Six years of Iranian Children with Congenital Hypothyroidism.

Intelligence Quotient at the Age of Six years of Iranian Children with Congenital Hypothyroidism.


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پژوهان
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نویسندگان: کورش اعتماد , حمید سوری , یداله محرابی

کلمات کلیدی: Management, Neonatal screening, Outcome

نشریه: Indian Pediatrics, 2,55,121 - 124,2018

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کد مقاله 66014745
عنوان فارسی مقاله Intelligence Quotient at the Age of Six years of Iranian Children with Congenital Hypothyroidism.
عنوان لاتین مقاله Intelligence Quotient at the Age of Six years of Iranian Children with Congenital Hypothyroidism.
نوع مقاله اصیل پژوهشی - Original Article
نحوه ایندکس شدن مقاله PMC - Pubmed Central
IF
عنوان نشریه Indian Pediatrics
نوع نشریه خارجی نمایه شده
شماره نشریه 2
دوره 55
صفحه شروع و پایان در نشریه 121 - 124
سال انتشار/ ارائه شمسی 1396
سال انتشار/ارائه میلادی 2018
آدرس لینک مقاله/ همایش در شبکه اینترنت https://www.ncbi.nlm.nih.gov/pubmed/28952455
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آدرس علمی (Affiliation) نویسنده متقاضی Department of Endocrinology and Metabolism, Ministry of Health, Tehran, Iran. Correspondence to: Dr Hamid Soori, Safety Promotion and Injury Prevention Research Center, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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Abstract OBJECTIVE: To evaluate the success rate of the National newborn screening program in maintenance of intelligent quotient (IQ) of children with congenital hypothyroidism in Iran. OBJECTIVE: Retrospective cohort study. METHODS: The IQ scores, in three subsets of verbal, non verbal (Performance) and full scale IQ, of 240 children diagnosed with Transient congenital hypothyroidism (TCH) and Permanent congenital hypothyroidism (PCH), from 5 provinces in 5 different geographical areas of Iran, were measured at the age of 6 years using revised Wechsler pre school and primary scale of intelligence and compared with 240 healthy children. We used independent sample t test and two-way ANOVA for data analysis. RESULTS: Mean of verbal, performance, and full scale IQ scores were lower in the CH cases (permanent and transient) than the control group. Most of the IQ differences in two studied groups related to the PCH cases (P=0.005). Mean difference of IQs between children in the two groups in Yazd province (center of Iran) was higher than other provinces, and they also had significantly lower IQ than their control (healthy) children (P=0.001). No treated child had IQ<70. CONCLUSION: Although mean IQs of CH children was lower than their controls, IQ of all treated CH cases were close to the healthy children. Comment in Prevention of Neurocognitive Impairment in Children Through Newborn Screening for Congenital Hypothyroidism. [Indian Pediatr. 2018]

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نویسنده نفر چندم مقاله
کورش اعتمادسوم
حمید سوریهفتم
یداله محرابیچهارم

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